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Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247826(4,5-bis(4-methoxyphenyl)isothiazole | CHEMBL473946)

IC50: 3nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)

IC50: 3nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
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Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)

IC50: 4.10nMAssay Description:Inhibition of bovine COX1 assessed as inhibition of calcium ionophore A23187-induced 12-hydroxyheptadecatrienoic acid formation by reverse-phase HPLC...More data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50245432(4,5-Bis(4-methoxyphenyl)-1,2-selenazole | CHEMBL47...)

IC50: 6nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247901(4-(4-Chlorophenyl)-5-p-tolyl-3H-1,2-dithiole-3-thi...)

IC50: 6nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

CHEMBL PC cid PC sid Patents Similars

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50245465(5-(4-Chlorophenyl)-4-(4-methoxyphenyl)-1,2-selenaz...)

IC50: 10nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247827(5-(4-methoxyphenyl)-4-p-tolylisothiazole | CHEMBL5...)

IC50: 10nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50245433(5-(4-Methoxyphenyl)-4-p-tolyl-1,2-selenazole | CHE...)

IC50: 20nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247851(4-(4-Chlorophenyl)-5-(4-methoxyphenyl)isothiazole ...)

IC50: 20nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50245466(4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-1,2-selenaz...)

IC50: 20nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247578(4-(4-Chlorophenyl)-5-p-tolyl-3H-1,2-dithiol-3-one ...)

IC50: 20nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247902(4,5-bis(4-methoxyphenyl)-3H-1,2-dithiole-3-thione ...)

IC50: 30nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247847(5-(4-Chlorophenyl)-4-p-tolylisothiazole | CHEMBL52...)

IC50: 40nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50245435(4-(4-Chlorophenyl)-5-p-tolyl-1,2-selenazole | CHEM...)

IC50: 50nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247850(5-(4-Chlorophenyl)-4-(4-methoxyphenyl)isothiazole ...)

IC50: 70nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247849(4,5-Bis(4-chlorophenyl)isothiazole | CHEMBL491088)

IC50: 100nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50038649(2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...)

IC50: 150nMAssay Description:Inhibition of bovine COX1 assessed as inhibition of calcium ionophore A23187-induced 12-hydroxyheptadecatrienoic acid formation by reverse-phase HPLC...More data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247577(5-(4-Chlorophenyl)-4-p-tolyl-3H-1,2-dithiol-3-one ...)

IC50: 200nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50245436(4,5-Bis(4-chlorophenyl)-1,2-selenazole | CHEMBL501...)

IC50: 200nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50245434(5-(4-Chlorophenyl)-4-p-tolyl-1,2-selenazole | CHEM...)

IC50: 200nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50038649(2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...)

IC50: 200nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247848(4-(4-Chlorophenyl)-5-p-tolylisothiazole | CHEMBL49...)

IC50: 200nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)

IC50: 350nMAssay Description:Inhibition of bovine COX-1 by enzyme immuno assayMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50387596(CHEMBL2057740)

IC50: 410nMAssay Description:Inhibition of bovine COX1 assessed as inhibition of calcium ionophore A23187-induced 12-hydroxyheptadecatrienoic acid formation by reverse-phase HPLC...More data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247574(4-(4-(Methylsulfonyl)phenyl)-5-p-tolyl-3H-1,2-dith...)

IC50: 600nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247852(4-(5-(4-Hydroxyphenyl)isothiazol-4-yl)phenol | CHE...)

IC50: 1.00E+3nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)

IC50: 1.10E+3nMAssay Description:Inhibition of bovine seminal vesicle microsomal COX1-mediated prostaglandin productionMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)

IC50: 1.30E+3nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)

IC50: 1.40E+3nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247900(5-(4-Chlorophenyl)-4-p-tolyl-3H-1,2-dithiole-3-thi...)

IC50: 2.00E+3nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)

IC50: 2.10E+3nMAssay Description:Inhibition of bovine COX1More data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50387594(CHEMBL2057741)

IC50: 2.50E+3nMAssay Description:Inhibition of bovine COX1 assessed as inhibition of calcium ionophore A23187-induced 12-hydroxyheptadecatrienoic acid formation by reverse-phase HPLC...More data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)

IC50: 2.90E+3nMAssay Description:Inhibition of bovine COX-1 by enzyme immuno assayMore data for this Ligand-Target Pair

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Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)

IC50: 2.90E+3nMAssay Description:Inhibition of bovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)

IC50: 3.30E+3nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 productionMore data for this Ligand-Target Pair

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Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50387595(CHEMBL2057739)

IC50: 3.60E+3nMAssay Description:Inhibition of bovine COX1 assessed as inhibition of calcium ionophore A23187-induced 12-hydroxyheptadecatrienoic acid formation by reverse-phase HPLC...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247897(5-(4-(methylsulfonyl)phenyl)-4-p-tolyl-3H-1,2-dith...)

IC50: 7.00E+3nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)

IC50: 7.70E+3nMAssay Description:Inhibition of bovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50387597(CHEMBL2057214)

IC50: 7.70E+3nMAssay Description:Inhibition of bovine COX1 assessed as inhibition of calcium ionophore A23187-induced 12-hydroxyheptadecatrienoic acid formation by reverse-phase HPLC...More data for this Ligand-Target Pair

CHEMBL PC cid PC sid

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50248698(1-(4-Methanesulfonylphenyl)-5-[4-(1-difluoromethyl...)

IC50: 7.80E+3nMAssay Description:Inhibition of bovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247576(5-(4-(Methylsulfonyl)phenyl)-4-phenyl-3H-1,2-dithi...)

IC50: 8.00E+3nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)

IC50: 8.00E+3nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50247608(4-(4-(Methylsulfonyl)phenyl)-5-phenyl-3H-1,2-dithi...)

IC50: 8.00E+3nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50248697(1-(4-Aminosulfonylphenyl)-5-(2-chloropyridin-4-yl)...)

IC50: 8.30E+3nMAssay Description:Inhibition of bovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)

IC50: 1.10E+4nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair

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KEGG PC cid PC sid PDB Patents Similars

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)

IC50: 1.30E+4nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 productionMore data for this Ligand-Target Pair

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CHEMBL DrugBank MCE
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PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50242349((5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaenoic ...)

IC50: 1.30E+4nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair

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PDB MMDB Reactome pathway KEGG
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B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50248699(1-(4-aminosulfonylphenyl)-5-[4-(1-difluoromethyl-1...)

IC50: 1.31E+4nMAssay Description:Inhibition of bovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Prostaglandin G/H synthase 1(Bos taurus)
Johannes Gutenberg University

Curated by ChEMBL

BDBM50210259((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hex...)

IC50: 1.50E+4nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair

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